STILLWATER, Okla. -- Jon Holland settled a 100-point game with a timely defensive play.
Holland intercepted B.J. Symons' pass with 1:05 left as Oklahoma State (No. 24 ESPN/USA Today, No. 23 AP) ended a furious comback by Texas Tech (No. 23 ESPN/USA Today) in a 51-49 victory Saturday.
Tatum Bell ran for a career-high 238 yards, with TD runs of 95, 48 and 5 yards, and the Cowboys (6-1, 2-1 Big 12) scored on their first eight possessions to take a 48-21 lead into the fourth quarter.
"The offense came out quickly with big plays by Tatum Bell and Rashaun Woods," Cowboys coach Les Miles said. "It gave us the opportunity to score and score repeatedly."
Symons was 42-of-67 for 552 yards, his sixth straight game with more than 400 yards. He threw five touchdown passes and ran for another score, but also had two interceptions and missed several open receivers.
"I personally feel like I let the team down," Symons said. "Obviously the game wasn't lost on that last play, but to fight so hard and come up short hurts."
Texas Tech, the nation's highest scoring team, got back in it with four fourth-quarter touchdowns, one after Joey Hawkins recovered an onside kick. The Red Raiders (5-2, 2-1) drove to the Oklahoma State 40 before Holland's interception.
Luke Phillips' 20-yard field goal with 5:43 remaining ended a 21-0 Texas Tech run as the Cowboys beat the Red Raiders for the first time in four tries.
"We understood that this would be a four-quarter game," Miles said. "The clock just doesn't seem to run when you play Texas Tech."
Oklahoma State's Josh Fields threw for 320 yards and a touchdown on 18-of-29 passing, moving into second place on the school's career passing list with 5,004 yards.
Woods had 147 yards on six catches in Oklahoma State's homecoming game, which lasted more than four hours with 97 passes and 20 penalties to stop the clock. It was Woods' 18th 100-yard game.
The teams combined for 1,334 total yards. Oklahoma State was third in the nation in scoring coming in, averaging 40.6 points. Texas Tech had averaged 46.8.
Bell, the Big 12's second-leading rusher, easily surpassed his season average of 107.8 yards. His 95-yard run through a huge hole up the middle was the third longest rush in Cowboys history.
Oklahoma State led 34-14 at halftime, scoring on all six possessions.
Tommy Devereaux scored from 14 yards on an end-around, and Fields hit Charlie Johnson from 4 yards out to put the Cowboys up 21-7. Jamar Ransom's midfield interception of Symons' pass set up Phillips 31-yard field goal with 3 seconds left in the half.
Symons threw first-half touchdown passes to Nehemiah Glover from 15 yards and Wes Welker from 14 yards. But the Red Raiders fell off the scoring pace when Keith Toogood missed a 33-yard field-goal try on the first possession.
"I think we played too tight," Texas Tech coach Mike Leach said. "I think we tried to make too much happen. In the second half, I think we settled down."
Welker led Texas Tech receivers with 129 yards and two scores on 10 catches. Taurean Henderson ran for 123 yards on nine carries and a TD. He also caught seven passes for 60 yards.
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